TLC-22620-21835 · OpenVSafe

Timeline

Registration Vaccinations Survey responses Call reports Cases without a report Call attempts Call successful Pregnancy survey

2021-04-06
Dose 1 — Pfizer-BioNTech
2021-04-27
Registered in v-safe
2021-04-27
Dose 2 — Pfizer-BioNTech
2021-04-27
Survey response — day 0, dose 2
MedDRA: Appendicectomy, Appendicitis — Feeling: Fair · Get care from a doctor or other healthcare professional · Emergency room or emergency department visit, Hospitalization

Free text: Systemic reaction (other): Appendicitis about 19 days after 1st injection · Healthcare visit (other): Surgery/ appendectomy

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-27
Report sent to call center — day 0, dose 2
Get care from a doctor or other healthcare professional

1 call case(s)
2021-04-28
Health check-in — days 1–6 daily, dose 2
Feeling: Poor · Site: Pain · Fever · Headache, Joint pains, Muscle or body aches, Fatigue or tiredness, Nausea, Abdominal pain · Be unable to do your normal daily activities

Adult check-in
2021-04-29
Health check-in — days 1–6 daily, dose 2
Feeling: Fair · Site: Pain · Fever · Headache, Nausea · Be unable to work

Adult check-in
2021-05-03
Health check-in — days 1–6 daily, dose 2
Feeling: Fair · Site: Pain · Headache, Fatigue or tiredness, Nausea

Adult check-in
2021-05-04
Survey response — day 7, dose 2
MedDRA: Ear pain — Feeling: Fair · Headache, Nausea

Free text: Earache

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-05-18
Survey response — day 21, dose 2
MedDRA: Arthralgia — Feeling: Fair

Free text: Bilateral Knee pain and ankle pain

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-05-25
Health check-in — day 28, dose 2
Feeling: Fair

Adult check-in
2021-07-29
Health check-in — 3 months, dose 2
Feeling: Poor

Adult check-in
2021-10-26
Survey response — 6 months, dose 2
MedDRA: Morning sickness — Feeling: Fair · Be unable to do your normal daily activities, Get care from a doctor or other healthcare professional · Telehealth, virtual health, or email health consultation, Outpatient clinic or urgent care clinic visit

Free text: Extreme Morning Sickness

MedDRA releases: 2024-11 · check-in free text available
2021-10-26
Report sent to call center — 6 months, dose 2
Be unable to do your normal daily activities · Get care from a doctor or other healthcare professional

Telehealth, virtual health, or email health consultation · Outpatient clinic or urgent care clinic visit · 1 call case(s)
2021-10-28
Call 1 — Left Voicemail

Vaccinations

Dose	Date	Manufacturer	Co-administered
1	2021-04-06	Pfizer-BioNTech
2	2021-04-27	Pfizer-BioNTech

Call center

2 call center cases

2 unsuccessful

See the call center timeline

Free text

Release 8 — day 0, dose 2

2021-04-27

Systemic reaction (other): Appendicitis about 19 days after 1st injection

Healthcare visit (other): Surgery/ appendectomy

Release 8 — day 7, dose 2

2021-05-04

Systemic reaction (other): Earache

Release 8 — day 21, dose 2

2021-05-18

Symptoms: Bilateral Knee pain and ankle pain

Release 10 — 6 months, dose 2

2021-10-26

Symptoms: Extreme Morning Sickness

Each entry is dated by the survey it was written in (the CDC re-sent the releases with survey dates in 2025); click a date to see that survey response. The CDC cut some text off at about 250 characters: symptoms in every release, and the other two fields in releases 9-12. Those entries are marked "cut off by CDC".

MedDRA terms by release

Field	Preferred term	2021-09	2023-04	2024-11
HCVO	Appendicectomy	✓	✓	✓
SD	Arthralgia	✓	✓	✓
SD	Morning sickness	·	·	✓
SRO	Appendicitis	✓	✓	✓
SRO	Ear pain	✓	✓	✓

✓ active code · ○ coded but marked inactive · blank = not in that release