2WJ-25666-13947

2 vaccinations 15 coded responses 21 check-ins 15 free-text entries 1 call case

Sex: Female
Age at first dose: 21-25
ZIP prefix: 028 / RI
Registered: 2021-03-14

Relationship: Self
Race: White
Ethnicity: Not Hispanic or Latino

Timeline

Registration Vaccinations Survey responses Call reports Cases without a report Call attempts Call successful Pregnancy survey

2021-03-14
Registered in v-safe
2021-03-14
Dose 1 — Pfizer-BioNTech
2021-03-14
Survey response — day 0, dose 1
MedDRA: Feeling abnormal — Feeling: Fair · Site: Pain · Fatigue or tiredness, Nausea

Free text: Brain Fog

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-03-15
Survey response — days 1–6 daily, dose 1
MedDRA: Feeling abnormal — Feeling: Fair · Site: Pain · Chills, Headache, Joint pains, Muscle or body aches, Fatigue or tiredness, Nausea, Vomiting, Abdominal pain · Be unable to do your normal daily activities

Free text: Brain Fog

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-03-16
Survey response — days 1–6 daily, dose 1
MedDRA: Feeling abnormal, Flushing — Feeling: Fair · Headache, Joint pains, Fatigue or tiredness, Nausea · Be unable to do your normal daily activities

Free text: Brain fog, flushing

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-03-18
Health check-in — days 1–6 daily, dose 1
Feeling: Good · Fatigue or tiredness, Nausea, Abdominal pain

Adult check-in
2021-03-19
Survey response — days 1–6 daily, dose 1
MedDRA: Feeling abnormal, Pruritus — Feeling: Fair · Chills, Headache, Fatigue or tiredness, Nausea

Free text: Brain fog, itching

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-03-20
Survey response — days 1–6 daily, dose 1
MedDRA: Condition aggravated, Gastrooesophageal reflux disease, Mast cell activation syndrome — Feeling: Good · Fatigue or tiredness, Nausea, Diarrhea

Free text: Reflux, MCAS aggravation

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-03-21
Health check-in — day 7, dose 1
Feeling: Good · Headache, Joint pains, Fatigue or tiredness

Adult check-in
2021-03-31
Survey response — day 14, dose 1
MedDRA: Crohn's disease, Postural orthostatic tachycardia syndrome — Feeling: Fair

Free text: My autoimmune disease (Crohns) seems to be aggravated slightly. My POTS is as well.

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-03
Dose 2 — Pfizer-BioNTech
2021-04-03
Survey response — day 0, dose 2
MedDRA: Feeling abnormal, Flushing, Oropharyngeal pain, Photosensitivity reaction — Feeling: Fair · Site: Pain, Redness · Fever · Chills, Headache, Joint pains, Muscle or body aches, Fatigue or tiredness, Nausea · Be unable to do your normal daily activities

Free text: Brain fog, flushing, photosensitivity, sore throat

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-05
Survey response — days 1–6 daily, dose 2
MedDRA: Feeling abnormal, Flushing, Hot flush, Muscle tightness, Tendon discomfort — Feeling: Poor · Site: Pain, Redness, Swelling · Fever · Chills, Headache, Joint pains, Muscle or body aches, Fatigue or tiredness, Abdominal pain · Be unable to do your normal daily activities

Free text: Flushing, hot flashes, brain fog, tendon/ligament/muscle tightness - feels light tight about to snap rubber bands (the same sensation as fluoroquin antibiotic rxn in hEDS)

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-06
Survey response — days 1–6 daily, dose 2
MedDRA: Cyanosis, Immune system disorder, Mast cell activation syndrome, Oxygen saturation decreased — Feeling: Poor · Site: Pain · Fever · Joint pains, Muscle or body aches, Fatigue or tiredness, Nausea, Abdominal pain · Be unable to do your normal daily activities

Free text: Worsening MCAS symptoms, lower Sp02 (91-95) with cyanosis noted around the lips

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-07
Survey response — days 1–6 daily, dose 2
MedDRA: Feeling abnormal — Feeling: Fair · Site: Pain · Joint pains, Fatigue or tiredness, Abdominal pain · Be unable to do your normal daily activities

Free text: Brain fog

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-08
Health check-in — days 1–6 daily, dose 2
Feeling: Fair · Muscle or body aches, Fatigue or tiredness, Diarrhea

Adult check-in
2021-04-09
Survey response — days 1–6 daily, dose 2
MedDRA: Muscle spasms — Feeling: Fair · Site: Pain · Fever · Joint pains, Muscle or body aches, Fatigue or tiredness · Be unable to do your normal daily activities

Free text: Muscle spasm

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-10
Survey response — day 7, dose 2
MedDRA: Flushing, Oropharyngeal pain — Feeling: Fair · Site: Pain · Fever · Joint pains, Muscle or body aches, Fatigue or tiredness, Nausea, Abdominal pain · Be unable to do your normal daily activities

Free text: Flushing, sore throat

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-18
Survey response — day 14, dose 2
MedDRA: Fatigue, Myositis — Feeling: Fair · Be unable to work, Be unable to do your normal daily activities

Free text: So much fatigue. My PT says my muscles are inflamed. Inflammatory conditions seem to be flaring more.

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-28
Survey response — day 21, dose 2
MedDRA: Crohn's disease, Oligomenorrhoea, Pre-existing disease — Feeling: Fair · Be unable to do your normal daily activities

Free text: My Crohns has been flaring pretty badly, my period was almost twice as long as normal, my MCAS and POTS are still re stabilizing.

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-05-08
Health check-in — day 35, dose 2
Feeling: Fair

Adult check-in
2021-05-15
Survey response — day 42, dose 2
MedDRA: Flushing, Headache, Nausea, Vomiting — Feeling: Poor · Be unable to do your normal daily activities, Get care from a doctor or other healthcare professional · Telehealth, virtual health, or email health consultation

Free text: Worsening vomiting/nausea. Flushing. Headache.

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-05-15
Report sent to call center — day 42, dose 2
Be unable to do your normal daily activities · Get care from a doctor or other healthcare professional

1 call case(s)
2021-07-03
Health check-in — 3 months, dose 2
Feeling: Poor

Adult check-in
2021-10-03
Health check-in — 6 months, dose 2
Feeling: Fair

Adult check-in
2022-05-06
Call 1 — Left Voicemail

Vaccinations

Dose	Date	Manufacturer	Co-administered
1	2021-03-14	Pfizer-BioNTech
2	2021-04-03	Pfizer-BioNTech

Call center

1 call center case

1 unsuccessful

1 wait over 3 months for a first call

See the call center timeline

Free text

Release 5 — day 0, dose 1

2021-03-14

Systemic reaction (other): Brain Fog

Release 5 — days 1–6 daily, dose 1

2021-03-15

Systemic reaction (other): Brain Fog

2021-03-16

Systemic reaction (other): Brain fog, flushing

2021-03-19

Systemic reaction (other): Brain fog, itching

Release 6 — days 1–6 daily, dose 1

2021-03-20

Systemic reaction (other): Reflux, MCAS aggravation

Release 6 — day 14, dose 1

2021-03-31

Symptoms: My autoimmune disease (Crohns) seems to be aggravated slightly. My POTS is as well.

Release 6 — day 0, dose 2

2021-04-03

Systemic reaction (other): Brain fog, flushing, photosensitivity, sore throat

Release 6 — days 1–6 daily, dose 2

2021-04-05

Systemic reaction (other): Flushing, hot flashes, brain fog, tendon/ligament/muscle tightness - feels light tight about to snap rubber bands (the same sensation as fluoroquin antibiotic rxn in hEDS)

Release 7 — days 1–6 daily, dose 2

2021-04-06

Systemic reaction (other): Worsening MCAS symptoms, lower Sp02 (91-95) with cyanosis noted around the lips

2021-04-07

Systemic reaction (other): Brain fog

2021-04-09

Systemic reaction (other): Muscle spasm

Release 7 — day 7, dose 2

2021-04-10

Systemic reaction (other): Flushing, sore throat

Release 7 — day 14, dose 2

2021-04-18

Symptoms: So much fatigue. My PT says my muscles are inflamed. Inflammatory conditions seem to be flaring more.

Release 8 — day 21, dose 2

2021-04-28

Symptoms: My Crohns has been flaring pretty badly, my period was almost twice as long as normal, my MCAS and POTS are still re stabilizing.

Release 8 — day 42, dose 2

2021-05-15

Symptoms: Worsening vomiting/nausea. Flushing. Headache.

Each entry is dated by the survey it was written in (the CDC re-sent the releases with survey dates in 2025); click a date to see that survey response. The CDC cut some text off at about 250 characters: symptoms in every release, and the other two fields in releases 9-12. Those entries are marked "cut off by CDC".

MedDRA terms by release

Field	Preferred term	2021-09	2023-04	2024-11
SD	Crohn's disease	✓	✓	✓
SD	Fatigue	✓	✓	✓
SD	Flushing	✓	✓	✓
SD	Headache	✓	✓	✓
SD	Myositis	✓	✓	✓
SD	Nausea	✓	✓	✓
SD	Oligomenorrhoea	✓	✓	✓
SD	Postural orthostatic tachycardia syndrome	✓	✓	✓
SD	Pre-existing disease	✓	✓	✓
SD	Vomiting	✓	✓	✓
SRO	Condition aggravated	✓	✓	✓
SRO	Cyanosis	✓	✓	✓
SRO	Feeling abnormal	✓	✓	✓
SRO	Flushing	✓	✓	✓
SRO	Gastrooesophageal reflux disease	✓	✓	✓
SRO	Hot flush	✓	✓	✓
SRO	Immune system disorder	·	·	✓
SRO	Mast cell activation syndrome	✓	✓	✓
SRO	Muscle spasms	✓	✓	✓
SRO	Muscle tightness	✓	✓	✓
SRO	Oropharyngeal pain	✓	✓	✓
SRO	Oxygen saturation decreased	✓	✓	✓
SRO	Photosensitivity reaction	✓	✓	✓
SRO	Pruritus	✓	✓	✓
SRO	Tendon discomfort	✓	✓	✓

✓ active code · ○ coded but marked inactive · blank = not in that release