2DT-66847-16683 · OpenVSafe

Timeline

Registration Vaccinations Survey responses Call reports Cases without a report Call attempts Call successful Pregnancy survey

2020-12-31
Registered in v-safe
2020-12-31
Dose 1 — Pfizer-BioNTech
2020-12-31
Health check-in — day 0, dose 1
Feeling: Fair · Site: Pain · Fatigue or tiredness

Adult check-in
2021-01-01
Health check-in — days 1–6 daily, dose 1
Feeling: Fair · Site: Pain · Fever · Chills, Muscle or body aches, Fatigue or tiredness, Nausea, Diarrhea

Adult check-in
2021-01-02
Health check-in — days 1–6 daily, dose 1
Feeling: Fair · Site: Pain · Muscle or body aches, Fatigue or tiredness

Adult check-in
2021-01-03
Health check-in — days 1–6 daily, dose 1
Feeling: Good · Site: Pain · Muscle or body aches, Fatigue or tiredness

Adult check-in
2021-01-05
Health check-in — days 1–6 daily, dose 1
Feeling: Good · None

Adult check-in
2021-01-06
Health check-in — days 1–6 daily, dose 1
Feeling: Good · None

Adult check-in
2021-01-07
Health check-in — day 7, dose 1
Feeling: Good · None

Adult check-in
2021-01-14
Health check-in — day 14, dose 1
Feeling: Good

Adult check-in
2021-01-20
Dose 2 — Pfizer-BioNTech
2021-01-21
Health check-in — days 1–6 daily, dose 2
Feeling: Poor · Site: Pain, Swelling · Fever · Chills, Headache, Muscle or body aches, Fatigue or tiredness · Be unable to work, Be unable to do your normal daily activities

Adult check-in
2021-01-22
Health check-in — days 1–6 daily, dose 2
Feeling: Fair · Site: Pain · Fatigue or tiredness

Adult check-in
2021-01-23
Health check-in — days 1–6 daily, dose 2
Feeling: Fair · Site: Pain · Fatigue or tiredness

Adult check-in
2021-01-24
Health check-in — days 1–6 daily, dose 2
Feeling: Good · None

Adult check-in
2021-01-25
Health check-in — days 1–6 daily, dose 2
Feeling: Good · None

Adult check-in
2021-01-26
Health check-in — days 1–6 daily, dose 2
Feeling: Good · Diarrhea

Adult check-in
2021-01-27
Health check-in — day 7, dose 2
Feeling: Good · None

Adult check-in
2021-02-03
Health check-in — day 14, dose 2
Feeling: Fair

Adult check-in
2021-02-10
Survey response — day 21, dose 2
MedDRA: Dyspepsia — Feeling: Fair

Free text: New/unusual dyspepsia

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-02-19
Health check-in — day 28, dose 2
Feeling: Good

Adult check-in
2021-02-24
Health check-in — day 35, dose 2
Feeling: Good

Adult check-in
2021-03-04
Health check-in — day 42, dose 2
Feeling: Good

Adult check-in
2021-04-21
Health check-in — 3 months, dose 2
Feeling: Good

Adult check-in
2021-07-21
Survey response — 6 months, dose 2
MedDRA: Herpes simplex, Pre-existing disease — Feeling: Fair

Free text: Significant increase in both frequency and volume of HSV outbreaks since vaccine - SPOUSE AS WELL (order of 5-10x).

MedDRA releases: 2024-11 · check-in free text available
2021-10-29
Dose 3 — Pfizer-BioNTech
2021-11-01
Health check-in — days 1–6 daily, dose 3
Feeling: Poor · Site: Pain · Fever · Chills, Headache, Joint pains, Muscle or body aches, Fatigue or tiredness, Nausea, Diarrhea, Abdominal pain · Be unable to work or attend school, Be unable to do your normal daily activities

Adult check-in
2021-11-04
Health check-in — days 1–6 daily, dose 3
Feeling: Good · Fatigue or tiredness

Adult check-in
2021-11-07
Health check-in — day 7, dose 3
Feeling: Good · None

Adult check-in
2021-11-12
Health check-in — day 14, dose 3
Feeling: Good

Adult check-in
2021-11-19
Health check-in — day 21, dose 3
Feeling: Good

Adult check-in
2021-12-11
Survey response — day 42, dose 3
MedDRA: Herpes simplex, Pre-existing disease, Skin disorder, Vaccine positive rechallenge — Feeling: Fair

Free text: Increased number/intensity of HSV outbreaks - like after the 2nd dose - including across bilateral dermatomes.

MedDRA releases: 2024-11 · check-in free text available
2022-01-30
Survey response — 3 months, dose 3
MedDRA: Condition aggravated, Pre-existing disease — Feeling: Fair

Free text: Increase in HSV outbreaks, including concomitant lesions bilaterally.

MedDRA releases: 2024-11 · check-in free text available
2022-10-31
Survey response — 12 months, dose 3
MedDRA: COVID-19, Herpes simplex, Pre-existing disease, Reaction to previous exposure to any vaccine — Feeling: Good

Free text: Progressively strong reactivation of HSV after each vaccination/booster and COVID infection. Definitely have seen correlation between COVID and HSV as per some literature (N of 1 trial).

MedDRA releases: 2024-11 · check-in free text available

Vaccinations

Dose	Date	Manufacturer	Co-administered
1	2020-12-31	Pfizer-BioNTech
2	2021-01-20	Pfizer-BioNTech
3	2021-10-29	Pfizer-BioNTech	No

Free text

Release 4 — day 21, dose 2

2021-02-10

Symptoms: New/unusual dyspepsia

Release 9 — 6 months, dose 2

2021-07-21

Symptoms: Significant increase in both frequency and volume of HSV outbreaks since vaccine - SPOUSE AS WELL (order of 5-10x).

Release 10 — day 42, dose 3

2021-12-11

Symptoms: Increased number/intensity of HSV outbreaks - like after the 2nd dose - including across bilateral dermatomes.

Release 11 — 3 months, dose 3

2022-01-30

Symptoms: Increase in HSV outbreaks, including concomitant lesions bilaterally.

Release 12 — 12 months, dose 3

2022-10-31

Symptoms: Progressively strong reactivation of HSV after each vaccination/booster and COVID infection. Definitely have seen correlation between COVID and HSV as per some literature (N of 1 trial).

Each entry is dated by the survey it was written in (the CDC re-sent the releases with survey dates in 2025); click a date to see that survey response. The CDC cut some text off at about 250 characters: symptoms in every release, and the other two fields in releases 9-12. Those entries are marked "cut off by CDC".

MedDRA terms by release

Field	Preferred term	2021-09	2023-04	2024-11
SD	Condition aggravated	·	·	✓
SD	COVID-19	·	·	✓
SD	Dyspepsia	✓	✓	✓
SD	Herpes simplex	·	·	✓
SD	Pre-existing disease	·	·	✓
SD	Reaction to previous exposure to any vaccine	·	·	✓
SD	Skin disorder	·	·	✓
SD	Vaccine positive rechallenge	·	·	✓

✓ active code · ○ coded but marked inactive · blank = not in that release