22F-31006-78910 · OpenVSafe

Timeline

Registration Vaccinations Survey responses Call reports Cases without a report Call attempts Call successful Pregnancy survey

2021-03-04
Dose 1 — Pfizer-BioNTech
2021-03-25
Registered in v-safe
2021-03-25
Dose 2 — Pfizer-BioNTech
2021-03-25
Health check-in — day 0, dose 2
Feeling: Good · None

Adult check-in
2021-03-26
Health check-in — days 1–6 daily, dose 2
Feeling: Fair · Site: Pain · Fever · Chills, Headache, Muscle or body aches, Fatigue or tiredness · Be unable to do your normal daily activities

Adult check-in
2021-03-27
Health check-in — days 1–6 daily, dose 2
Feeling: Good · Site: Pain · Fatigue or tiredness

Adult check-in
2021-03-28
Health check-in — days 1–6 daily, dose 2
Feeling: Good · Diarrhea

Adult check-in
2021-03-29
Health check-in — days 1–6 daily, dose 2
Feeling: Good · None

Adult check-in
2021-03-30
Health check-in — days 1–6 daily, dose 2
Feeling: Good · None

Adult check-in
2021-03-31
Health check-in — days 1–6 daily, dose 2
Feeling: Good · None

Adult check-in
2021-04-01
Health check-in — day 7, dose 2
Feeling: Good · Chills

Adult check-in
2021-04-08
Health check-in — day 14, dose 2
Feeling: Good

Adult check-in
2021-04-15
Health check-in — day 21, dose 2
Feeling: Fair

Adult check-in
2021-04-22
Survey response — day 28, dose 2
MedDRA: Menstrual disorder — Feeling: Fair · Get care from a doctor or other healthcare professional · Telehealth, virtual health, or email health consultation

Free text: I have a very different menstrual cycle than I had previously.

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-04-22
Report sent to call center — day 28, dose 2
Get care from a doctor or other healthcare professional

1 call case(s)
2021-04-29
Survey response — day 35, dose 2
MedDRA: Heavy menstrual bleeding, Menstruation irregular — Feeling: Good

Free text: My menstruation cycle has restarted - 2 weeks late - with a heavy flow

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-05-06
Health check-in — day 42, dose 2
Feeling: Good

Adult check-in
2021-06-24
Survey response — 3 months, dose 2
MedDRA: Fatigue, Menstruation irregular, Tinnitus, Unevaluable event — Feeling: Good · Get care from a doctor or other healthcare professional

Free text: Symptoms: I have not had a regular period in the past two- three months since my second shot. I have also been very tired and have tinnitus. · Healthcare visit (other): I am going to schedule a visit with my OB and my GP

MedDRA releases: 2021-09,2023-04,2024-11 · check-in free text available
2021-06-24
Report sent to call center — 3 months, dose 2
Get care from a doctor or other healthcare professional

1 call case(s)
2021-06-28
Call successful
Participant prefers to complete VAERS report online
2021-09-23
Health check-in — 6 months, dose 2
Feeling: Fair

Adult check-in
2021-10-05
Dose 3 — Pfizer-BioNTech
2022-03-25
Health check-in — 12 months, dose 2
Feeling: Good

Adult check-in
2022-04-05
Dose 4 — Pfizer-BioNTech
2022-04-28
Survey response — day 21, dose 4
MedDRA: Menstruation delayed — Feeling: Fair

Free text: I had a delayed menstrual cycle. Usually every 3 weeks 5 days. Was 7 weeks between cycles.

MedDRA releases: 2024-11 · check-in free text available
2022-05-03
Health check-in — day 28, dose 4
Feeling: Fair

Adult check-in
2022-05-10
Health check-in — day 35, dose 4
Feeling: Fair

Adult check-in
2022-05-17
Health check-in — day 42, dose 4
Feeling: Fair

Adult check-in
2022-07-05
Health check-in — 3 months, dose 4
Feeling: Fair

Adult check-in
2022-10-04
Survey response — 6 months, dose 4
MedDRA: Menstruation irregular — Feeling: Good

Free text: My menstrual cycle continues to be off track

MedDRA releases: 2024-11 · check-in free text available
2023-04-07
Health check-in — 12 months, dose 4
Feeling: Good

Adult check-in

Vaccinations

Dose	Date	Manufacturer	Co-administered
1	2021-03-04	Pfizer-BioNTech
2	2021-03-25	Pfizer-BioNTech
3	2021-10-05	Pfizer-BioNTech	No
4	2022-04-05	Pfizer-BioNTech	No

Call center

2 call center cases

2 successful

See the call center timeline

Free text

Release 7 — day 28, dose 2

2021-04-22

Symptoms: I have a very different menstrual cycle than I had previously.

Release 8 — day 35, dose 2

2021-04-29

Symptoms: My menstruation cycle has restarted - 2 weeks late - with a heavy flow

Release 9 — 3 months, dose 2

2021-06-24

Symptoms: I have not had a regular period in the past two- three months since my second shot. I have also been very tired and have tinnitus.

Healthcare visit (other): I am going to schedule a visit with my OB and my GP

Release 11 — day 21, dose 4

2022-04-28

Symptoms: I had a delayed menstrual cycle. Usually every 3 weeks 5 days. Was 7 weeks between cycles.

Release 12 — 6 months, dose 4

2022-10-04

Symptoms: My menstrual cycle continues to be off track

Each entry is dated by the survey it was written in (the CDC re-sent the releases with survey dates in 2025); click a date to see that survey response. The CDC cut some text off at about 250 characters: symptoms in every release, and the other two fields in releases 9-12. Those entries are marked "cut off by CDC".

MedDRA terms by release

Field	Preferred term	2021-09	2023-04	2024-11
HCVO	Unevaluable event	✓	✓	✓
SD	Fatigue	✓	✓	✓
SD	Heavy menstrual bleeding	✓	✓	✓
SD	Menstrual disorder	✓	✓	✓
SD	Menstruation delayed	·	·	✓
SD	Menstruation irregular	✓	✓	✓
SD	Tinnitus	✓	✓	✓

✓ active code · ○ coded but marked inactive · blank = not in that release